上海招聘

We are looking for a motivated person to join our Protein Structural Biology Group as the lab head of the Protein Science Research at the China Novartis Institutes for Biomedical Research. The candidate will be part of the drug discovery research team to express, purify and characterize protein, protein complex and substrate for the needs of assay development, target validation and structural biology studies. The candidate will be responsible for managing internal protein science group as well as outsourcing resources to efficiently and effectively deliver superior protein biochemistry results to facilitate hits finding and leads optimization projects. The candidate will also develop innovative technologies including assays and analytic tools to understand protein-protein and protein-ligand interactions. The candidate will analyze scientific results, provide oral and written reports, and remain current with regard to literature reports and technological developments.

Candidates must hold Ph.D in Biochemistry, chemistry, Structural Biology or related field with track record of publications in protein and structural biology fields. Expertise in expression protein from E.coli, baculovirus and mammalian cells is absolutely required. The ideal candidate should have several years of industry working experiences in drug discovery, in-depth knowledge and hands-on technical skills in characterizing protein-protein and protein-ligand interactions. The candidate must be familiar with protein X-ray crystallographic and/or NMR technology including crystallization, small molecular screen, data collection, structure determination, refinement and analysis. The candidate should be able to utilize various biochemical and biophysical technologies including TR-FRET, FP, Biacore and ITC to analyze protein-ligand interaction to understand the mechanism of action of the inhibition molecule. The successful candidate is expected to have strong work ethic, excellent oral and written communication in English, and ability to function in an interdisciplinary team setting are essential.

诺华（Novartis AG）是全球医药保健行业的领导者。其核心业务涉及专利药，非专利药，眼睛护理，消费者保健和动物保健等领域。诺华公司总部设在瑞士巴塞尔，业务遍及全球140多个国家和地区。

诺华（中国）生物医学研究有限公司是诺华全球研发组织――诺华生物医学研究所（NIBR）的第八个研究基地。我们位于中国上海市张江高科技园区，将成为诺华在亚洲的主要研究中心，以及除在欧美的研究中心外的最主要的研究中心。我们的研究和探索开发活动的重点是发现并开发创新疗法，用于治疗在亚洲远未达到医药需求的疾病。我们与从不同之处在于将专注现代药物的发现和开发方法的研究。最初阶段，研发工作将专注在引起中国地方性癌症的感染原因。我们还将开展临床试验，进行安全性研究，生物标志物和检测分析，表达谱、生物分析以及转化医学的研究。

随着公司业务的迅速扩展，我们热忱欢迎您的加入。同时我们将提供具有竞争力的薪酬福利待遇以及良好的培训发展机会。